{"id":20112,"date":"2020-10-09T10:56:51","date_gmt":"2020-10-09T10:56:51","guid":{"rendered":"https:\/\/clon.genehtik.com\/?p=20112"},"modified":"2020-10-09T10:56:51","modified_gmt":"2020-10-09T10:56:51","slug":"covid-cannabis-thc","status":"publish","type":"post","link":"https:\/\/genehtik.com\/fr\/actualidad-cannabis\/covid-cannabis-thc\/","title":{"rendered":"Le principe actif du cannabis pourrait att\u00e9nuer les effets graves de la COVID-19."},"content":{"rendered":"

Pour lutter contre certaines complications respiratoires graves de la Covid, le principe actif du cannabis THC<\/strong> Le t\u00e9trahydrocannabinol (THC) pourrait \u00eatre efficace. C'est ce que sugg\u00e8rent des \u00e9tudes ind\u00e9pendantes men\u00e9es par des \u00e9quipes scientifiques.<\/p>\n

Cela impliquerait l'administration contr\u00f4l\u00e9e du principe actif du cannabis, et non la consommation de la plante elle-m\u00eame.<\/p>\n

Les \u00e9tudes les plus r\u00e9centes ont \u00e9t\u00e9 publi\u00e9es par des chercheurs de l'Universit\u00e9 de Caroline du Sud, sous la direction d'Amira Mohamed et Mitzi Nagarkatti.<\/p>\n

Publi\u00e9 dans Fronti\u00e8res de la pharmacologie<\/a>, Les auteurs expliquent qu'ils n'ont pas \u00e9tudi\u00e9 les effets du THC sur la Covid-19, mais sur le syndrome de d\u00e9tresse respiratoire aigu\u00eb (SDRA), une complication grave pouvant survenir apr\u00e8s une infection par cette bact\u00e9rie. Staphylocoque dor\u00e9<\/em>.<\/p>\n

Dans cette exp\u00e9rience, des souris ont \u00e9t\u00e9 expos\u00e9es \u00e0 l'ent\u00e9rotoxine produite par cette bact\u00e9rie, appel\u00e9e SEB, qui est hautement toxique pour l'organisme. 100% des personnes ayant re\u00e7u du THC ont \u00e9t\u00e9 gu\u00e9ries<\/strong>.<\/p>\n

Ce qui am\u00e8ne les chercheurs \u00e0 penser que le THC pourrait \u00e9galement \u00eatre utile dans certaines complications respiratoires graves de la COVID-19, c'est qu'ils partagent un m\u00e9canisme d'action similaire. Le SEB (bromure s\u00e9rique) d\u00e9clenche une importante r\u00e9action immunitaire appel\u00e9e orage cytokinique, impliquant des prot\u00e9ines cl\u00e9s de la communication cellulaire. Ces prot\u00e9ines jouent un r\u00f4le tr\u00e8s actif dans le syst\u00e8me immunitaire.<\/p>\n

Il a \u00e9t\u00e9 observ\u00e9 que la COVID-19 provoque une importante lib\u00e9ration de cytokines, une r\u00e9action excessive du syst\u00e8me immunitaire. C'est ce qui conduit g\u00e9n\u00e9ralement \u00e0 des l\u00e9sions pulmonaires et \u00e0 une d\u00e9faillance multivisc\u00e9rale.<\/p>\n

Ils \u00e9mettent donc l'hypoth\u00e8se que le THC pourrait \u00e9galement \u00eatre utile contre la Covid-19. En effet, une proportion importante de patients atteints de Covid-19 souffrent de SDRA.<\/p>\n

Les auteurs pr\u00e9cisent\u00a0: \u201c\u00a0Des \u00e9tudes suppl\u00e9mentaires sont n\u00e9cessaires pour d\u00e9terminer si les m\u00e9canismes impliqu\u00e9s sont similaires et si les cannabino\u00efdes peuvent \u00eatre utilis\u00e9s pour traiter le Covid associ\u00e9 au SDRA.\u00a0\u201d<\/p>\n

D\u00e9but des essais cliniques sur l'homme<\/h2>\n

Les m\u00eames chercheurs ont publi\u00e9 les r\u00e9sultats de l'\u00e9tude dans les revues Journal international des sciences mol\u00e9culaires<\/a> y Journal britannique de pharmacologie<\/a>.<\/p>\n

Selon Nagarkatti, dans les dizaines d'exp\u00e9riences compil\u00e9es par les trois \u00e9tudes, Les souris 100% ayant re\u00e7u du THC ont \u00e9t\u00e9 gu\u00e9ries.<\/strong>.<\/p>\n

Les auteurs indiquent que les r\u00e9sultats sont suffisamment prometteurs pour envisager des essais cliniques. Cependant, ils soulignent que, pour le moment, la participation des personnes d\u00e9j\u00e0 atteintes de la Covid-19 est d\u00e9conseill\u00e9e.<\/p>\n

En juin, un article d'une \u00e9quipe italienne a \u00e9t\u00e9 publi\u00e9 dans le British Journal of Pharmacology. Parmi les auteurs figure Walter Sanseverino, de la soci\u00e9t\u00e9 de bioinformatique Sequentia Biotech, bas\u00e9e \u00e0 Barcelone.<\/p>\n

Les chercheurs ont \u00e9mis l'hypoth\u00e8se que le cannabinol, \u00e9galement pr\u00e9sent dans le cannabis mais diff\u00e9rent du THC, et qui poss\u00e8de lui aussi des propri\u00e9t\u00e9s analg\u00e9siques et anti-inflammatoires, pourrait \u00eatre utile contre les complications respiratoires de la Covid-19. Ils ont fond\u00e9 leur hypoth\u00e8se sur les donn\u00e9es de plusieurs \u00e9tudes pr\u00e9cliniques.<\/p>\n

D'autres substances \u00e0 base de cannabis font l'objet d'\u00e9tudes en lien avec la Covid-19.<\/h2>\n

Une troisi\u00e8me \u00e9quipe de scientifiques a publi\u00e9 une \u00e9tude en avril. \u00e9tude pr\u00e9liminaire en attente d'\u00e9valuation<\/a>. Olga, Igor Kovalchuk et leurs collaborateurs de l'Universit\u00e9 de Lethbridge, en Alberta (Canada), soulignent que les extraits de cannabis \u00e0 forte teneur en cannabidiol et faible teneur en THC pourraient bloquer le r\u00e9cepteur que le coronavirus SARS-CoV-2 utilise pour entrer dans les cellules.<\/p>\n

L'objectif initial \u00e9tait de d\u00e9velopper des extraits pour traiter divers probl\u00e8mes de sant\u00e9, mais lorsque la pand\u00e9mie est apparue, ils ont revu les donn\u00e9es pour les adapter \u00e0 la Covid-19.<\/p>\n

Igor Kovalchuk l'explique de mani\u00e8re tr\u00e8s imag\u00e9e dans le magazine. Th\u00e9rapie au cannabis<\/a>\u201c Nous imaginons une cellule comme un grand b\u00e2timent. Les cannabino\u00efdes r\u00e9duisent le nombre de portes par un facteur de 70%. De cette fa\u00e7on, le niveau d'entr\u00e9e est limit\u00e9. Par cons\u00e9quent, les chances de combattre l'infection sont accrues. \u201d.<\/p>\n

Enfin, d'autres compos\u00e9s pr\u00e9sents dans le cannabis pourraient \u00e9galement \u00eatre utiles. Il s'agit des terp\u00e8nes, des compos\u00e9s que l'on retrouve dans de nombreuses autres plantes.<\/p>\n

L'\u00e9tude a \u00e9t\u00e9 men\u00e9e par deux soci\u00e9t\u00e9s isra\u00e9liennes\u00a0: Eybna, sp\u00e9cialis\u00e9e dans les terp\u00e8nes, et Cannasoul, qui effectue des recherches sur le cannabis et ses d\u00e9riv\u00e9s.<\/p>\n

L'enqu\u00eate, qui a \u00e9t\u00e9 rapport\u00e9e par plusieurs m\u00e9dias, tels que Sant\u00e9 Europe<\/a>, L'\u00e9tude note que les terp\u00e8nes pr\u00e9sents dans le cannabis \u00e9taient \u00e9galement efficaces contre les processus inflammatoires, notamment la temp\u00eate de cytokines produite par la Covid-19.<\/p>\n

L'objectif est de trouver un dispositif permettant l'administration de terp\u00e8nes par inhalation.<\/p>\n

Toutes ces \u00e9tudes visent \u00e0 v\u00e9rifier l'effet de certains principes actifs administr\u00e9s de mani\u00e8re contr\u00f4l\u00e9e, et non les effets du tabagisme du cannabis. Les m\u00e9decins ont averti que fumer du cannabis provoque une inflammation des poumons, ce qui repr\u00e9sente un risque accru de complications li\u00e9es \u00e0 la COVID-19.<\/p>\n

Fontaine: CCMA (Soci\u00e9t\u00e9 catalane des m\u00e9dias audiovisuels)<\/a><\/p>\n

N'oubliez pas que dans notre banque de graines de marijuana<\/strong> Genehtik, vous pouvez acqu\u00e9rir plusieurs g\u00e9n\u00e9tique de qualit\u00e9 et garantie<\/a>.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

Para combatir algunas complicaciones respiratorias graves de la Covid el principio activo del cannabis THC (tetrahidrocannabinol) podr\u00eda ser efectivo. Esto lo se\u00f1alan estudios independientes hechos por equipos cient\u00edficos. Se tratar\u00eda de la administraci\u00f3n de forma controlada del principio activo del cannabis y no del consumo…<\/p>","protected":false},"author":1,"featured_media":20118,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"bwfblock_default_font":"","footnotes":""},"categories":[313],"tags":[],"class_list":["post-20112","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualidad-cannabis"],"yoast_head":"\nEl principio activo del cannabis podria paliar efectos graves de la Covid<\/title>\n<meta name=\"description\" content=\"Para combatir algunas complicaciones respiratorias graves de la Covid el principio activo del cannabis THC (tetrahidrocannabinol) podr\u00eda ser efectivo.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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